In scouts my son’s nickname was “Jimmy Ziplock” because of his packing technique. I find zip lock type bags to be a life saver. Even though I like things organized I am not particularly gifted at achieving it, and even worse at keeping things organized. I use packing cubes some, but I really like to use ordinary zip lock type bags for many items since they can keep things clean and dry, and you can see through them.
I can see what is in them and they can keep liquids from spreading if they escape their bottles. I once had a bottle of lotion pop from the heat in the trunk of a car in New Mexico and now I always put such things into a zip lock.

I can group things, like my camera accoutrements, that go together into them and see where I put things. They are also handy for keeping electrical cords from wandering around and snagging random things. It is useful for going through airports to have all electrical stuff in one bag and all battery type things in another. It makes it easier for TSA agents if they want to look at something more closely.
I like to bring washcloths with me, they make convenient little towels or can be used to clean things or as eye compresses, zip locks are great for keeping them clean before use and containing the dirt and moisture from use afterwards.

The really big ones are useful packaging if you are out in drenching weather (for example in Japan during typhoon season). They are about the right size to use as a daypack liner. Those big ones are also useful if you are traveling somewhere with interesting fauna (creepy crawlies). We used them in rural Kenya to keep dust and bugs at bay.
Yes, ziplock bags. Put clothes in them. Shirts in one for example, u derwear in another. Then squeeze all the air out of them. Lie down on them to get all air out. 3 gallon bags are good for this and can be bought maybe on line but available in USA. Once all air out, zip it up and clothes don’t take up as much room in case and don’t move.
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We like those big ones a lot!
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I also use ziplock bags when packing and also shower caps for shoes. The free ones you get in hotels are the best
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I always grab the shower caps if they have them. They can be extremely useful in many situations.
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